Olmesartan Medoxomil+chlorthalidone
About Olmesartan Medoxomil+chlorthalidone
Chlorthalidone+olmesartan Medoxomil belongs to the class of medicines called antihypertensives primarily used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart diseases, irregular heartbeat, and other complications.
Chlorthalidone+olmesartan Medoxomil is a combination of two medicines namely: Olmesartan medoxomil and Chlorthalidone. Olmesartan medoxomil is an angiotensin receptor blocker (ARB) which works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Chlorthalidone is a diuretic or water pills that removes extra water and certain electrolytes from the body. Together it lowers fluid overload, blood pressure and improves blood flow.
You can take Chlorthalidone+olmesartan Medoxomil with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience headache, nausea, or dizziness. Most of these side effects of Chlorthalidone+olmesartan Medoxomil do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and can increase the risk of getting heart diseases and stroke. Inform your doctor if you are suffering from any kidney or liver or heart disease or are diabetic. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Chlorthalidone+olmesartan Medoxomil can be prescribed accordingly. Do not use Chlorthalidone+olmesartan Medoxomil if you are unable to urinate, are dehydrated, have low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine. Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body.
Uses of Olmesartan Medoxomil+chlorthalidone
Medicinal Benefits
Chlorthalidone+olmesartan Medoxomil is a combination medication, generally used when a single medicine is not effective in controlling blood pressure. Chlorthalidone+olmesartan Medoxomil is used to treat hypertension, where Olmesartan medoxomil works by relaxing the blood vessels. On the other hand, Chlorthalidone being diuretic works by increasing the amount of urine that is passed out from the kidneys and hence lowering the blood pressure. Together it lowers the overall raised blood pressure and reduces the risk of having a heart attack, stroke, or kidney problems.
Directions for Use
Storage
Side Effects of Olmesartan Medoxomil+chlorthalidone
- Bradycardia (slow heart rate)
- Cold extremities
- Gastrointestinal disturbances including nausea
- Fatigue
Drug Warnings
Chlorthalidone+olmesartan Medoxomil should not be given to the people allergic to Chlorthalidone+olmesartan Medoxomil, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women, or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Chlorthalidone+olmesartan Medoxomil can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Chlorthalidone+olmesartan Medoxomil and breastfeeding.
Drug Interactions
Drug-Drug Interaction: Chlorthalidone+olmesartan Medoxomil may interact with other high blood pressure-lowering pills (benazepril, metoprolol, ramipril, hydrochlorothiazide, simvastatin, diltiazem, verapamil, azilsartan, benazepril, lisinopril, amiloride), and can lower your blood pressure leading to severe condition. Besides this, medicine to treat erectile dysfunction (sildenafil), antibiotics (clarithromycin, erythromycin, rifampicin), antifungal (itraconazole, ketoconazole), anti-HIV drugs (ritonavir), anti-epilepsy medicines (carbamazepine, phenytoin, phenobarbital, primidone), immune-suppressing drugs (cyclosporine, tacrolimus), and pain killers (ibuprofen, aspirin) should not be taken with Chlorthalidone+olmesartan Medoxomil.
Drug-Food Interaction: Chlorthalidone+olmesartan Medoxomil severely interacts with grapefruit, grapefruit juices, and St. John’s wort (a plant used to treat depression). Hence it should not be taken with Chlorthalidone+olmesartan Medoxomil.
Drug-Disease Interaction: Chlorthalidone+olmesartan Medoxomil should not be given to people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease, renal impairment, or heart failure.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Chlorthalidone+olmesartan Medoxomil to avoid unpleasant side-effects.
Pregnancy
unsafeChlorthalidone+olmesartan Medoxomil should not be taken until prescribed. Chlorthalidone+olmesartan Medoxomil is a Category C/D pregnancy drug which is considered unsafe for pregnant women. Chlorthalidone+olmesartan Medoxomil can have some harmful effects on the baby (foetus), Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast Feeding
unsafeChlorthalidone+olmesartan Medoxomil is not recommended in breastfeeding mothers. It is excreted into milk in small amounts and is cleared slowly. It can accumulate in the infant, especially newborns or preterm infants. Lactation might also be suppressed due to the effect of Chlorthalidone+olmesartan Medoxomil.
Driving
unsafeIt is not recommended to drive after taking Chlorthalidone+olmesartan Medoxomil as it may occasionally cause drowsiness or fatigue.
Liver
cautionChlorthalidone+olmesartan Medoxomil to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionChlorthalidone+olmesartan Medoxomil to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
unsafeUse of Chlorthalidone+olmesartan Medoxomil in children less than 1 year of age is not recommended as the safety and efficacy of Chlorthalidone+olmesartan Medoxomil in these age groups have not yet been established.
Habit Forming
Diet & Lifestyle Advise
Keep your weight under control with BMI 19.5-24.9.
Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
If you are taking alcohol then only one serving for women and two servings for men is advisable.
Quitting smoking is the best strategy to lower the risk of heart disease.
Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.
Special Advise
When pregnancy is detected, discontinue Chlorthalidone+olmesartan Medoxomil as drugs that act directly on the renin-angiotensin system can cause severe injury and even death to the developing fetus (unborn baby).
Patients Concern
Disease/Condition Glossary
Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.
FAQs
Chlorthalidone+olmesartan Medoxomil is used to treat high blood pressure. It works by relaxing blood vessels, this allows the blood to flow more smoothly and the heart to pump more efficiently. Chlorthalidone+olmesartan Medoxomil also removes extra water and certain electrolytes from the body. Thereby, it lowers fluid overload and blood pressure.
Taking Chlorthalidone+olmesartan Medoxomil may cause dehydration. So, to avoid dehydration, drink plenty of fluids and inform your doctor if you feel extremely thirsty.
It's unlikely that Chlorthalidone+olmesartan Medoxomil affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There's not enough evidence to say for certain. For best advise, consult your doctor.
In case, you have missed a dose of Chlorthalidone+olmesartan Medoxomil, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both the doses together. Take only one dose, taking a double dose of Chlorthalidone+olmesartan Medoxomil will lead to low blood pressure.
Chlorthalidone+olmesartan Medoxomil can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions and one should not abruptly discontinue it without discussing it with a doctor.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Chlorthalidone+olmesartan Medoxomil is a combination of two medicines namely: Olmesartan medoxomil and Chlorthalidone. Olmesartan medoxomil is an angiotensin receptor blocker (ARB) that works by blocking the hormone angiotensin, thereby relaxing blood vessels. Chlorthalidone is a diuretic or water pill that removes extra water and certain electrolytes from the body. Together they lower fluid overload, blood pressure and improve blood flow.
The time it takes for Chlorthalidone+olmesartan Medoxomil to work may vary depending on individual factors, such as the severity of hypertension and overall health. Usually, we observe improvements in blood pressure control within a week of starting treatment. With continued use, Chlorthalidone+olmesartan Medoxomil can help control high blood pressure throughout your life.
You can take Chlorthalidone+olmesartan Medoxomil at any time of day, but it's preferable to take it in the morning. Consistency is key, so try to take it at the same time every day. Most importantly, follow your doctor's instructions and take Chlorthalidone+olmesartan Medoxomil exactly as directed.
Taking Chlorthalidone+olmesartan Medoxomil can cause dizziness in some people. This is usually mild and temporary. To minimize this risk, take Chlorthalidone+olmesartan Medoxomil as directed, get up slowly, and avoid standing for long periods. If you experience severe or persistent dizziness, contact your doctor. Always consult your doctor if you have concerns about side effects or taking Chlorthalidone+olmesartan Medoxomil.
While using Chlorthalidone+olmesartan Medoxomil, consider making lifestyle changes to help manage your blood pressure and overall health. Maintain a healthy weight, exercise for at least 30 minutes a day, and eat a balanced diet rich in whole grains, fruits, vegetables, and low-fat dairy products. Limit your sodium intake and alcohol consumption, and quit smoking if you haven't already. Manage stress through mindfulness practices and social support, and monitor your blood pressure daily. Additionally, include omega-3 rich foods in your diet and use low-fat oils like olive, soybean, canola, and coconut oil for cooking. Remember to consult your doctor for personalized advice on making these lifestyle changes to ensure you're taking the best care of your health.
Chlorthalidone+olmesartan Medoxomil is not typically associated with weight gain and does not significantly affect body weight. However, it's important to remember that individual results may vary. If you have specific concerns or questions, it's always best to consult with your healthcare provider for personalized guidance and care.
Although rare, Chlorthalidone+olmesartan Medoxomil may cause serious side effects in a few individuals. These severe reactions include swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, as well as severe diarrhea, weight loss, difficulty breathing or swallowing, hoarseness, sore throat with fever, unusual bleeding or bruising, and severe skin rash with peeling skin. If you experience any of these symptoms, seek medical attention promptly. Your doctor will assess the risks and recommend the best course of action to relieve them.
Generally, Chlorthalidone+olmesartan Medoxomil is considered safe for long-term use, as it is often prescribed to manage conditions like high blood pressure, which may require lifelong treatment. In fact, many people take Chlorthalidone+olmesartan Medoxomil for extended periods to maintain healthy blood pressure and reduce the risk of cardiovascular complications as directed by the doctor. However, it's essential to regularly consult with your doctor to monitor your response to the medication, adjust dosages as needed, and minimize potential side effects.
Tell your doctor you're taking Chlorthalidone+olmesartan Medoxomil before surgery. They may ask you to stop taking it for a while to ensure your safety. This is because Chlorthalidone+olmesartan Medoxomil can lower blood pressure. Follow your doctor's advice to avoid any problems.
Common side effects of Chlorthalidone+olmesartan Medoxomil include dizziness, bradycardia (slow heart rate), cold extremities, headache, hypotension (low blood pressure), and nausea. While these side effects may be uncomfortable, they often have a minimal impact and may subside over time. However, if your symptoms worsen or become severe, consult your doctor promptly. They will assess your situation and provide guidance on managing your side effects, which may include adjusting your treatment plan to minimize your discomfort.
